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Vaccination: Influenza Vaccine

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Total 6915 results found since Jan 2013.

Experts with links to drugs industry 'hyped swine flu'
Conclusion This was a well-conducted study, albeit based on a small sample of articles. The finding that academics with ties to the drugs industry were more likely to make a higher assessment of risk from swine flu, and those promoting the use of antiviral drugs were more likely to have industry links, is worrying. The general issue of academics with undisclosed links to the pharmaceutical industry being interviewed by journalists is of concern. That said, the study does not prove that media coverage either fuelled public anxiety about swine flu or the policy decisions made about drug or vaccine funding. Similarly, the...
Source: NHS News Feed - November 12, 2013 Category: Consumer Health News Tags: Medical practice Medication Swine flu Source Type: news

The Genetics of Life and Death: Virus-Host Interactions Underpinning Resistance to African Swine Fever, a Viral Hemorrhagic Disease
Conclusion and Future Perspectives The mechanisms which result in reduced viral replication and lack of disease in African wild suids after ASFV infection are largely unknown. The data so far indicate that this is not due to an intrinsic difference in the ability of the virus to replicate in macrophages from these hosts. A more likely explanation is that the innate immune system of these hosts is better able to control virus replication resulting in a reduced systemic infection and reduced pathogenesis. This may involve a balance between virus and host factors which has evolved over long term infections of these hosts. Se...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

Swine flu jab narcolepsy risk is very small
Conclusion This study confirms that the Pandemrix vaccine against swine flu is associated with a very small risk of narcolepsy in children and young people. As the authors point out, this risk may have been overestimated if children with narcolepsy who had been vaccinated were more rapidly referred than others because of increased awareness of the link. The methods used were practical for a rapid assessment of risk, but as this was essentially a case series analysis they are limited by a number of factors: The rates calculated are dependent on the accurate diagnosis and identification of the cases of narcolepsy. By usin...
Source: NHS News Feed - February 27, 2013 Category: Consumer Health News Tags: Medication Medical practice Swine flu Source Type: news

Live poultry market workers are susceptible to both avian and swine influenza viruses, Guangdong Province, China
Publication date: Available online 25 September 2015 Source:Veterinary Microbiology Author(s): Jidang Chen, Jun Ma, Sarah K. White, Zhenpeng Cao, Yun Zhen, Shuyi He, Wanjun Zhu, Changwen Ke, Yongbiao Zhang, Shuo Su, Guihong Zhang Guangdong Province is recognized for dense populations of humans, pigs, poultry and pets. In order to evaluate the threat of viral infection faced by those working with animals, a cross-sectional, sero-epidemiological study was conducted in Guangdong between December 2013 and January 2014. Individuals working with swine, at poultry farms, or live poultry markets (LPM), and veterinaria...
Source: Veterinary Microbiology - September 25, 2015 Category: Veterinary Research Source Type: research

Serological study of influenza viruses in veterinarians working with swine in Mexico
AbstractHumans and swine are both affected by influenza viruses, and swine are considered a potential source of new influenza viruses. Transmission of influenza viruses across species is well documented. The aim of this study was to evaluate the seroprevalence of different influenza virus subtypes in veterinarians working for the Mexican swine industry, using a hemagglutination inhibition test. All sera tested were collected in July 2011. The data were analysed using a generalized linear model and a linear model to study the possible association of seroprevalence with the age of the veterinarian, vaccination status, and bi...
Source: Archives of Virology - February 22, 2017 Category: Virology Source Type: research

Insulated Isothermal Reverse Transcriptase PCR (iiRT‐PCR) for Rapid and Sensitive Detection of Classical Swine Fever Virus
In this study, we describe validation of a new probe‐based insulated isothermal reverse transcriptase PCR (iiRT‐PCR) assay for rapid detection of classical swine fever virus (CSFV) on a compact, user‐friendly device (POCKIT™ Nucleic Acid Analyzer) that does not need data interpretation by the user. The assay accurately detected CSFV RNA from a diverse panel of 33 CSFV strains representing all three genotypes plus an additional in vitro‐transcribed RNA from cloned sequences representing a vaccine strain. No cross‐reactivity was observed with a panel of 18 viruses associated with livestock including eight other ...
Source: Transboundary and Emerging Diseases - January 28, 2015 Category: Veterinary Research Authors: O. Lung, J. Pasick, M. Fisher, C. Buchanan, A. Erickson, A. Ambagala Tags: Original Article Source Type: research

Serological Evidence and Risk Factors for Swine Influenza Infections among Chinese Swine Workers in Guangdong Province
by Mengmeng Ma, Benjamin D. Anderson, Tao Wang, Yingan Chen, Dingmei Zhang, Gregory C. Gray, Jiahai Lu During July to September 2014, we performed a controlled, cross-sectional, seroepidemiologic study among 203 swine workers and 115 control subjects in Guangdong Province. Sera were tested using a hemagglutination inhibition assay against locally-isolated swine H3N2 and H1N1 viruses and commercially-obtained human influenza viral antigens. We found swine workers had a greater prevalence and odds of seropositivity against the swine H3N2 virus (17.3% vs. 7.0%; adjusted OR, 3.4; 95% CI, 1.1 -10.7). Younger age, self-report o...
Source: PLoS One - May 27, 2015 Category: Biomedical Science Authors: Mengmeng Ma et al. Source Type: research

Insulated Isothermal Reverse Transcriptase PCR (iiRT ‐PCR) for Rapid and Sensitive Detection of Classical Swine Fever Virus
In this study, we describe validation of a new probe‐based insulated isothermal reverse transcriptase PCR (iiRT‐PCR) assay for rapid detection of classical swine fever virus (CSFV) on a compact, user‐friendly device (POCKIT™ Nucleic Acid Analyzer) that does not need data interpretation by the user. The assay accurately detected CSFV RNA from a diverse panel of 33 CSFV strains representing all three genotypes plus an additional in vitro‐transcribed RNA from cloned sequences representing a vaccine strain. No cross‐reactivity was observed with a panel of 18 viruses associated with livestock including eight other ...
Source: Transboundary and Emerging Diseases - January 26, 2015 Category: Veterinary Research Authors: O. Lung, J. Pasick, M. Fisher, C. Buchanan, A. Erickson, A. Ambagala Tags: Original Article Source Type: research

Protective Efficacy of an Orf Virus-Vector Encoding the Hemagglutinin and the Nucleoprotein of Influenza A Virus in Swine
This study demonstrates the potential of ORFV-based vector for control of swine influenza virus in swine.
Source: Frontiers in Immunology - November 5, 2021 Category: Allergy & Immunology Source Type: research

C-reactive protein, haptoglobin, serum amyloid A and pig major acute phase protein response in pigs simultaneously infected with H1N1 swine influenza virus and Pasteurella multocida
Conclusions: The results of current study confirmed that monitoring of APP may revealed ongoing infection, and in this way may be useful in selecting clinically healthy pigs (i.e. before integration into an uninfected herd). Present results corroborated our previous findings that SAA could be a potentially useful indicator in experimental infection studies (e.g. vaccine efficiency investigations) or as a marker for disease severity, because of correlation observed between its concentration in serum and disease severity (lung scores, clinical scores).
Source: BMC Veterinary Research - Latest articles - January 18, 2013 Category: Veterinary Research Authors: Malgorzata Pomorska-MólIwona Markowska-DanielKrzysztof KwitKatarzyna StepniewskaZygmunt Pejsak Source Type: research

HA1-2-fljB Vaccine Induces Immune Responses against Pandemic Swine-Origin H1N1 Influenza Virus in Mice
In 2009, a novel pandemic swine-origin influenza A (H1N1) virus caused a public emergency of international concern. Vaccination is the primary strategy for the control of influenza epidemics. However, the poor immunopotency of many vaccine antigens is a major barrier to the development of effective vaccines against influenza. Flagellin, a Toll-like receptor 5 (TLR5) ligand, has been used as an adjuvant to enhance the immunopotency of vaccines in preclinical studies. Here, we developed a recombinant candidate vaccine, HA1-2-fljB, in which the globular head of the hemagglutinin (HA) antigen (residues 62-284) from H1N1 virus ...
Source: Journal of Molecular Microbiology and Biotechnology - October 7, 2016 Category: Microbiology Source Type: research

Swine Flu, Bird Flu And Pandemic Vaccination
As the world prepares for what may be the next pandemic strain of influenza virus, in the H7N9 bird flu, a new UC Irvine study reveals that the 2009 H1N1 swine flu pandemic was deadliest for people under the age of 65, while those 65 and over had greater immunity due to previous exposure to similar viruses. Deaths from flu pandemics tend to skew younger than those from seasonal flu because of "antigenic recycling," or the fact that some parts of flu viruses have already made the rounds...
Source: Health News from Medical News Today - May 25, 2013 Category: Consumer Health News Tags: Swine Flu Source Type: news

Five Ways to Fight the Swine Flu
View the Swine Flu video here.   Winter in North America brings with it yearly uninvited guests- flu bugs- multiple strains of illness causing viruses just waiting for new bodies to infect.   The most common recommendation has been to protect yourself with a flu vaccine.  But with virtually all the US flu suddenly resistant to the leading antiviral Tamiflu, health officials are worried about where this could lead.  Here are some key guidelines you MUST know if you want to survive this year’s flu season.   How can you distinguish a cold from the flu? First understand that colds are minor infections of the nose and t...
Source: Dr. Donna, MedicineWoman - January 25, 2009 Category: Medical Scientists Authors: Dr. Donna Tags: breaking news Personal Health public health flu influenza pandemic prevention swine flu tamiflu treatment Source Type: blogs

Novel Human-like Influenza A Viruses Circulate in Swine in Mexico and Chile
Discussion Through new surveillance efforts and phylogenetic analysis of IAV-S in Mexico and Chile, we have expanded our understanding of the extensive IAV-S diversity that circulates in swine in Latin America. Most notably, we have identified multiple novel clades of H3N2 and H1N1 viruses of human origin in Mexico and Chile that have not been identified in swine previously, highlighting the importance of the human-swine interface in the evolution of IAV-S diversity in Latin America. The presence of two different IAV-S lineages in Mexico that are related to North American IAV-S (classical H1N1 and H3-cluster IV) also demon...
Source: PLOS Currents Outbreaks - August 13, 2015 Category: Epidemiology Authors: minelson22 Source Type: research

A recombinant chimeric influenza virus vaccine expressing the consensus H3 hemagglutinin elicits broad hemagglutination inhibition antibodies against divergent swine H3N2 influenza viruses
This study focuses on the hemagglutinin (HA) consensus-based approach towards developing a more broadly protective swine influenza vaccine against various H3 strains circulating in domestic pig populations. By computationally analyzing >1000 swine H3 full-length HA sequences, we generated a consensus H3 and expressed it in the context of influenza A WSN/33 reverse genetics system. The derived recombinant chimeric swine influenza virus with the consensus H3 was inactivated and further evaluated as a potential universal vaccine in pigs. The consensus H3 vaccine elicited broadly active hemagglutination inhibition (HI) anti...
Source: Vaccine - September 9, 2023 Category: Allergy & Immunology Authors: Jieshi Yu Chithra Sreenivasan Zhizhang Sheng Shao-Lun Zhai Jared W Wollman Sisi Luo Chen Huang Rongyuan Gao Zhao Wang Radhey S Kaushik Jane Christopher-Hennings Eric Nelson Ben M Hause Feng Li Dan Wang Source Type: research